Mark 3:5
He looked around at them in anger and, deeply distressed at their stubborn hearts . . .
Jesus knew that the religious leaders of His day did not want to believe that He was their Messiah. They wanted a strong military leader, not this meek, humble Teacher. Their mis-use of God's laws angered Him, but He was "deeply distressed at their stubborn hearts." It distressed Him deeply that they could see Him and perceive His power to heal and over demons, yet they were too stubborn in their own self-importance to accept who He was. Sin angers Him, but our own poor choices break His heart.
Even so, come, Lord Jesus!
