Death

John 11:33, 35, 38

When Jesus saw [Mary] weeping, and the Jews who had come along with her also weeping, he was deeply moved in spirit and troubled....Jesus wept...Jesus, once more deeply moved, came to the tomb.

Lazarus was one of Jesus' best friends. Jesus would lodge at Lazarus' home when He was in the area, and appreciated him. When Lazarus died, even though He knew what He would do, Jesus was very troubled that this enemy, Death, would have such a strong hold on His friend. When Jesus confronted Death in Lazarus, He was deeply moved.

John 12:27

Now my heart is troubled, and what shall I say, "Father, save me from this hour"? No, it was for this very reason that I came to this hour. "Father, glorify Your Name!"

Even when talking about His own death, Jesus was troubled.

God is never pleased with Death, it is our enemy, and God loves us. So much that He allowed His own Son to go through death in order to conquer it. The last enemy to be destroyed is Death.